Epigenetics and Codon Usage of the Histone Genes in 12 Drosophila Species

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Epigenetics and Codon Usage of the Histone Genes in 12 Drosophila Species

Histones are proteins that bind to DNA and form nucleosomes. There are several types of histones that differ in chromosome distribution and timing of their expression. In Drosophila, each canonical type histone is identical or highly similar in amino acid sequence to its corresponding replacement type histone; however, gene structure and codon usage differ between the two types of histones. Ide...

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Synonymous codons are not used at random, significantly influencing the base composition of the genome. The selection-mutation-drift model proposes that this bias reflects natural selection in favor of a subset of preferred codons. Previous estimates in Drosophila of the intensity of selective forces involved seem too large to be reconciled with theoretical predictions of the level of codon bia...

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ژورنال

عنوان ژورنال: Journal of Phylogenetics & Evolutionary Biology

سال: 2017

ISSN: 2329-9002

DOI: 10.4172/2329-9002.1000178